DPCstruct | MC18709

Metacluster Properties and Pfam Annotations

Number of structural domains12069
Mean domain length (aa)154 ± 28 aa
Standard deviation of domain lengths27.61
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.12
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.34
Mean intra-cluster sequence similarity (%)10.50
Pfam Score33.95
Assigned Pfam label(s) CL0103- CL0219- CL0001- PF01973- CL0045

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A853PKU2 229-390 EGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQGANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKE…
A0A7T3RCY4 251-393 NLVSDSSFETGRLGEWKLNGDSTACFVENNKNNAHSGKWTYKYWKSTGFKSTLTRKITGLSEGTYILSLWAMGGGGENNIRLFAANF…
A0A4S2MLX4 7-201 None
A0A1S8W315 378-529 None
A0A1R0YLB9 58-223 None
G8SIY4 4-133 None
A0A1Q9C683 453-601 None
A0A3L7PBV6 698-838 None
A0A1S8VGX2 6-157 None
A0A3L7PNC5 249-406 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.