DPCstruct | MC18648

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)110 ± 4 aa
Standard deviation of domain lengths4.42
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score89.00
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)44.37
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R6ZXX2 2-103 HALRLAGVDFSVPEADLRDWLSNPSFTPYPAITGALIKMLGGKQLRRSVFIDVIVFNYEHAPGASSPRRMADVDLDLLAKAIVKGHN…
A0A1I4V5M7 7-114 PEATIRALDGVGVDFSIPKSALTDFLGNAEFTPYPALSAGLLSLLDGRMLQRPVFLDVIVFNYEHSPGDPSPRRLEDVVFEVLKAAI…
E3IWN8 316-420 None
A0A1H5EYR5 418-529 None
A0A437LXZ6 509-626 None
A0A0B2YW87 7-114 None
A0A559TW12 15-122 None
A0A7H8J116 604-710 None
A0A2T2ZH22 754-862 None
A0A1H5KCP1 363-467 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.