DPCstruct | MC18639

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)69 ± 4 aa
Standard deviation of domain lengths4.20
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score88.70
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.94
Mean intra-cluster local Distance Difference Test score0.92
Mean intra-cluster sequence similarity (%)44.40
Pfam Score100.00
Assigned Pfam label(s) PF00696

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A379D783 1-72 MGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDMLRALLDNHIVPVINENDARRHQRNQGRRQ
A0A6B2LLT7 94-164 RACAAAGQSGMMSLYDDMFSQKGVAISQILLTENDFRNPQVRKHLQDTLNVLLKWNVVPIINENDVITTRT
A0A2S5TMC6 55-119 None
H3H1G1 29-101 None
T2JZE0 1-65 None
X0PGW2 20-80 None
A0A0A9D2K8 6-76 None
A0A177VRG1 25-89 None
A0A099DAX8 12-85 None
A0A142G094 21-94 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.