DPCstruct | MC18629

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)107 ± 11 aa
Standard deviation of domain lengths10.89
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score91.04
Mean fraction of residues predicted as intrinsically disordered0.54
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)47.83
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3S5DMW5 12-122 MAKSVEDTLFFRQNMGLALNEVGAEPVTHHFSIERFHHEMKTRQARQPDALSGTSTHDTKRGEDARARLYTLTEAPEQWSECLARWR…
A0A535NEW3 195-289 AVMAKGVEDTAFYRYNRLVSLNEVGGDPGSFGRSVEAFHAHCLKTSEKWPATMLTLSTHDTKRSGDVRARTNLLSEIPAEWESAVRR…
A0A017HLI0 120-206 None
A0A532E898 459-586 None
A0A0K2RQK0 70-164 None
A0A379AHG0 1-111 None
A0A6N9YFC3 80-169 None
A0A6I1IRG6 86-194 None
A0A257NYG6 1-111 None
A0A538DLK1 117-224 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.