DPCstruct | MC18620

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)137 ± 10 aa
Standard deviation of domain lengths9.97
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score89.89
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)36.96
Pfam Score93.75
Assigned Pfam label(s) CL0291- CL0260

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A346R0I1 262-395 YEVDFRLRPSGNAGPLATRFAGFADYQREKAWTWEHMALTRARVIAGDADLWERTTAVIEDVLCAPRDIVALRRDVASMRARIEAEK…
A0A833NKW4 1-128 LRPSGEAGLLVTSLKAYEHYQLKSAWLWEHQALVRARSIAGDEALCQKFEIFRREILTQSRDEAYVREEVLKMRQKMKDHLGSSSEQ…
A0A350XPR8 414-547 None
A0A533X9K7 315-463 None
C8XBY0 281-415 None
A0A336NCB7 105-239 None
A0A523LYP7 394-538 None
A0A831YD38 398-544 None
A0A6N3UDR1 38-176 None
A0A1F0CZP1 353-489 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.