DPCstruct | MC18605

Metacluster Properties and Pfam Annotations

Number of structural domains108
Mean domain length (aa)90 ± 14 aa
Standard deviation of domain lengths14.19
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.07
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)42.86
Pfam Score40.00
Assigned Pfam label(s) PF00122- CL0137

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J8FEG7 13-110 IPISLYVSIELVKLGQVFFLHHDLDLYDEETDSPIQCRALNITEDLGQIQHIFSDKTGTLTENRMVFRRCTVMGREYPHQENAKRLE…
A0A0R3SLN2 15-94 HTIIPISLQVTLEVVRFVQALFINWDLDMYDAKTNTPAMARTSNLNEDLGQVKYIFSDKTGTLTKNVMKFKMCSIGRDAY
A0A821SW20 57-152 None
W0TYM0 580-675 None
A0A4Y2V7C1 5-91 None
A0A6G0QMA7 2-87 None
A0A7J7E2P7 54-163 None
A0A2U1PYS1 152-235 None
A0A3Q3VWB9 364-444 None
H8Z9I2 321-396 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.