DPCstruct | MC1858

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)127 ± 11 aa
Standard deviation of domain lengths10.84
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score87.98
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)23.82
Pfam Score100.00
Assigned Pfam label(s) PF14325

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A9WL24 3-112 TSPNRLLATIFGAVYLLVGILGFFVTSGIGFAGTKGNNLIIFAVNPLHNVIHLAIGAALLLAGLSSTTAAKGVNVAVGAVYLLVGIV…
A0A2D6EVW1 3-111 LQKKFATGLGAVLLIVGIWGFVANSVLIFDVNTAHNVLHVITGVLGLAAGLGAGAQAKTFNVIFGLVYALVTVLGLLNVASVVNLLN…
A0A2V5ZSP4 60-200 None
A0A7Y3CTC1 34-176 None
A0A3B0C875 17-137 None
A0A6G3ZPV4 7-134 None
A0A254QDS2 48-175 None
A0A4R4AB69 2-114 None
A0A2R6E2N9 6-130 None
A0A7Y2QZK1 8-138 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.