DPCstruct | MC18544

Metacluster Properties and Pfam Annotations

Number of structural domains62
Mean domain length (aa)116 ± 19 aa
Standard deviation of domain lengths19.38
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score75.79
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)35.76
Pfam Score76.17
Assigned Pfam label(s) CL0229- CL0257- PF02135

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A822CJU6 11-114 IPSHPAVNDINDLIECDLMDTGNVFLSFACDKNYEFSSLRRAKFSTMGLLYELHTSTTEKFIYSCNTCRQQCDIRYHCTICEDFDLC…
A0A820G7H2 12-116 ISYPTVNDTNDLVQCDLMNSGNTFLNFARNENYEFSSLRRAKFSTMALLYELHTSATNKFTYYCNTCQQECDIHFHCALCEDFDLCE…
A0A2P4YSK5 73-227 None
A0A2P4YRA1 74-201 None
A0A820T2W6 78-259 None
A0A2G3CEJ9 4-125 None
A0A1B0BU47 26-130 None
A0A7S2RDY8 280-411 None
A0A7R9U6P2 958-1053 None
A0A0L9UT52 492-605 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.