DPCstruct | MC18540

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)209 ± 24 aa
Standard deviation of domain lengths23.92
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score88.27
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)24.99
Pfam Score88.24
Assigned Pfam label(s) CL0433- CL0666

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812ZIE1 132-411 ALTLGPLDYVRVRDAMDGTERAVHGPRLFFLGPYEKMQASGQGVSVSNMQYVLIEDKQTGERKVQRGPLVWIPGPREEGKVCNAVRL…
A0A822BXG1 1-192 MGCCKSTQYGCCIAIDHDESIILNKPTGKEIRYGPGWFCFPNWWDAQVMKSIPLQNNQYIIVKHIIDTDDKNAFHARNDIPLTQRTT…
A0A7J7ZXN8 1-174 None
A0A2H1BV94 8-193 None
A0A2V2V3C4 18-238 None
A0A812UG54 115-328 None
A0A812SYK5 7-187 None
L8GWT3 28-265 None
A0A813FVX3 100-275 None
A0A6G3Z6Z4 7-218 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.