DPCstruct | MC18533

Metacluster Properties and Pfam Annotations

Number of structural domains333
Mean domain length (aa)187 ± 35 aa
Standard deviation of domain lengths34.93
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score87.37
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)18.72
Pfam Score59.59
Assigned Pfam label(s) CL0040- CL0094- PF02272- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I2R1Z2 8-131 YRLMRLHFAAELVLEHVYQFFHHPEKIGANINEDKARIDFYWEGSIATIFPELTQRVNQMITEDLPIISAFSDEQNQRRYWRIEGFA…
A0A533VU45 440-623 DTGKLGGGRVLEVLKEGEEIFHVLDQPPSFKVGDSVRGILDWERRYRIMKMHTTAHILSAIVNRETGALITGNQIGPEESRLDLSLE…
A0A380QCL3 294-500 None
R5IML2 150-298 None
A0A1E3H6T4 419-616 None
A0A803Q536 238-461 None
A0A6J7I4Z3 152-417 None
A0A0R3U1J9 79-311 None
B6DTC6 631-819 None
A0A7M5V147 115-312 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.