DPCstruct | MC18510

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)126 ± 24 aa
Standard deviation of domain lengths23.62
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score73.41
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)29.24
Pfam Score100.00
Assigned Pfam label(s) CL0045

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6U4H457 17-135 FRAPLKVGGKVGSRVARLPARAVAPSVTALSARKAAEEEIDFWQGDWVCADCGYIYDRGECNGLYFEEQPRGFRCPQCRGPRRRYAK…
A0A2W1JWL6 1-108 MSSETKTNTSLKRYECKSCGYVYEPKEGDSRRDIPVGTPFEELPEDWTCPVCRAETKQFMDIGSVGAPSGFQENLGYGIGVNSLTPG…
A0A6P6B230 14-159 None
I1I2U1 58-203 None
A0A835PUG8 27-132 None
A0A7S4C8I3 136-244 None
A0A7R9UJY1 21-149 None
K8ETI6 2-159 None
M1UPH1 76-231 None
A0A218XW95 128-246 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.