DPCstruct | MC18491

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)153 ± 24 aa
Standard deviation of domain lengths23.91
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.42
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)26.97
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A024UA99 2-142 IRRLKEKWGMTYTSYEANWRMWASSILKLPVYQHDMHVANPPPEIMLHLFEPVPNGAQQRNQSLQRSMTVALDIVDSCLDGLGSLKR…
A0A418CAT8 51-182 ENKASYANAPREWSSVHQAMVVQLKKKWGSVYHASEAAWRIWAAGILKKPLYLHAANVGMAPPSNVLPSLQRVLRVADKRLAQHNMH…
A0A6G0WVQ5 39-235 None
A0A2P4X8M0 3-164 None
A0A182G1D7 84-263 None
A0A6G0S9Q6 4-127 None
W2I7E1 109-243 None
D0NZY7 21-144 None
A0A1Y2CQE0 406-547 None
A0A182G4K0 10-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.