DPCstruct | MC18478

Metacluster Properties and Pfam Annotations

Number of structural domains53
Mean domain length (aa)87 ± 12 aa
Standard deviation of domain lengths12.04
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score85.44
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)35.59
Pfam Score100.00
Assigned Pfam label(s) CL0491

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R8YML2 7-82 RMKVLSLYKSLLRESQKFSSYNFRMYALRKIRDEFREKKLLTDPARIKEEINFAEKNLGIIKRQVIVGNLYSTEKL
F2U1M6 1-77 MRSQALSLYRRMLREAQGFVSYNVRSYAVRRVREGFRQAKGEADPAVLENMFSKAKEDLEMLKRQRVVYQLYAHPSG
A0A5P1FG12 10-98 None
A0A194VLU7 4-81 None
A0A2A6CRZ8 42-124 None
A0A2R8MXG3 250-331 None
A0A1E3J671 34-152 None
A0A7D8Z378 1-105 None
A0A8A3P217 9-104 None
A0A2V5HSW0 6-95 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.