DPCstruct | MC18465

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)57 ± 3 aa
Standard deviation of domain lengths2.82
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score78.68
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)72.67
Pfam Score100.00
Assigned Pfam label(s) CL0431

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0X8P1 2-57 QEPYPSVKNILLLDSEGKRVAVKYYADDWPTQAAKLAFEKSVFTKTQKTNARTEAE
A0A287M3I0 36-91 MAPCPSVKNILVLDAEGKRVAVKYYADDWPSASSKMAFEKSLFVKTQKTSARAEGE
A0A453FW48 2-60 None
A0A6A1VZI7 531-586 None
A0A6A3CEY2 301-358 None
A0A438JNX6 1-56 None
A0A1R3JMR5 1-64 None
A0A2P2KAF0 8-62 None
A0A176WE36 120-174 None
A0A7N2LN11 48-104 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.