DPCstruct | MC18455

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)184 ± 37 aa
Standard deviation of domain lengths37.46
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score72.71
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)36.72
Pfam Score98.53
Assigned Pfam label(s) CL0063- PF04759

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3N7GDF9 2-159 VIGTIFGNRRGHVWFCIQHDRLSTIPLLLLELSIPTHQLVKEMQCGLVRLALECNRSELNSVPLRAVPVWTVNCNGKKAGFALRRKA…
A0A287L5Z1 147-383 EASMAFSSTCRSFHSEDLVSPPPKPLKQHRKNTKLGRTAVSRLRTALAAAISGRHRQVGLGSRLTGTLYGHRRGHVHLAFQVDPRAC…
A0A2R6XAG0 36-241 None
A0A834Z522 534-712 None
A0A7J7GNA1 178-336 None
M4CKA0 70-260 None
A0A5D2A698 31-233 None
A0A0Q3PDL4 2-217 None
A0A811MM02 41-209 None
A0A6P5GHK8 36-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.