DPCstruct | MC18433

Metacluster Properties and Pfam Annotations

Number of structural domains44
Mean domain length (aa)121 ± 19 aa
Standard deviation of domain lengths18.64
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score82.75
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)25.50
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I2GCB2 442-547 QQYLSGKSCQVKFGLTCGQFTFAIPQGLELEFKQGDQVVIQFHLASSEHPRKHVGDARGTDPACRLAVSISGHDGQGRFHAWLLVKG…
A0A7U2QSS8 6-113 RQNAHRVSCSDFEFTISRRLQLGVKVGDEVMLQFQLTETLNPEMYATKASIRDPASRLAVSIKGKGANGDYFVWLKNDGEKTVMIMN…
A0A830IP23 217-366 None
A0A395MEI8 135-253 None
B6QD95 181-304 None
A0A6A6I0V8 13-111 None
A0A162KMR0 329-442 None
A0A4Q4Z1D7 752-889 None
A0A1V6SRJ8 707-841 None
A0A1L9TZV5 2-99 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.