DPCstruct | MC18430

Metacluster Properties and Pfam Annotations

Number of structural domains62
Mean domain length (aa)125 ± 12 aa
Standard deviation of domain lengths12.39
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score84.25
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)39.51
Pfam Score98.08
Assigned Pfam label(s) PF12359- PF12340

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2K0TVX9 15-137 NAVRRYITQWDMSGKEIEAVEKSPFWHESTINHVLLLRGLFASGILSFVFAQKRWRVNYGLDPNREKTTKLAVPFRAKDNPTPRSEF…
A0A7U2MP34 13-144 GFWGPGTRDVLFLLRGLFAGGILVFAFGLKRWRVNYGLTSTREPSTKLAVPYRAKDSPTARSEYSHPDAVIVLTCLSWYYGGLSNED…
A0A0D2G9G7 97-228 None
F4PXJ5 1-128 None
A0A822DX26 473-630 None
H0EN30 476-593 None
A0A2K0UV93 1021-1140 None
A0A834S6Q8 102-239 None
A0A820T5Z1 131-257 None
A0A842Z362 8-141 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.