DPCstruct | MC18429

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)171 ± 16 aa
Standard deviation of domain lengths16.17
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score86.30
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)20.83
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2C9BR87 2-177 VDARFARRQATLSCAIIRNIAFYYAGWVTGDGQGRLKDDTDVGRTINSNFIDVAVLEWSKLFVDWEAKHHWRRFVKDTEARTAFRSG…
A0A101LJJ0 2-184 DRTKLLTCAEMNCMSFVKNLALSGATREQLGRGKVLSNFWSQISRNALDLAVLDWCHAFGQQKDALHWKNVFPDDEEAFRESMLTWM…
A0A3P3VMU7 30-199 None
A0A356R542 1-203 None
A0A378JRE6 94-249 None
A0A2A4ZW97 4-142 None
A0A0D5NLQ6 1-154 None
A0A1E7IGP6 1-176 None
H8W5A8 56-236 None
D8P5Y2 7-179 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.