DPCstruct | MC18402

Metacluster Properties and Pfam Annotations

Number of structural domains2711
Mean domain length (aa)188 ± 38 aa
Standard deviation of domain lengths37.58
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.68
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.68
Pfam Score93.39
Assigned Pfam label(s) PF10307- CL0029- CL0255- CL0137- PF18143

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T2WZB0 224-400 None
A0A8A9Y1Z0 466-681 None
K4Z7Q4 4-122 None
A0A2K0X4K5 191-416 None
A0A2T7PCB5 75-219 None
A0A7Z0HP40 2-156 None
A0A4Q2D6A0 254-404 None
A0A507FGD1 4-266 None
A0A507FJR2 3-213 None
A0A6B1CEQ9 24-240 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.