DPCstruct | MC18402

Metacluster Properties and Pfam Annotations

Number of structural domains2711
Mean domain length (aa)188 ± 38 aa
Standard deviation of domain lengths37.58
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.68
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.68
Pfam Score93.39
Assigned Pfam label(s) PF10307- CL0029- CL0255- CL0137- PF18143

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y5I6Y0 445-618 None
A0A7J7NS02 87-266 None
A0A2V8HNY0 623-791 None
A0A484DRN4 194-373 None
A0A1V4SX93 79-255 None
A0A6S9KLT1 52-368 None
K8Y791 459-632 None
A0A1Y1ZU48 76-275 None
A0A1Y1ZZ50 401-604 None
A0A1Y2CHD6 131-436 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.