DPCstruct | MC18402

Metacluster Properties and Pfam Annotations

Number of structural domains2711
Mean domain length (aa)188 ± 38 aa
Standard deviation of domain lengths37.58
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.68
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.68
Pfam Score93.39
Assigned Pfam label(s) PF10307- CL0029- CL0255- CL0137- PF18143

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S1E277 816-1039 None
W7WDI3 2-147 None
A0A150H0W8 2-217 None
A0A365GWV1 1-122 None
A0A6H5K6D0 24-247 None
A0A6H5K7Y8 18-181 None
A0A1Z5THI7 45-259 None
A0A1Z5TQ81 786-1057 None
A0A1Z5TRZ5 2-197 None
A0A3M1VHT6 57-284 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.