DPCstruct | MC18402

Metacluster Properties and Pfam Annotations

Number of structural domains2711
Mean domain length (aa)188 ± 38 aa
Standard deviation of domain lengths37.58
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.68
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.68
Pfam Score93.39
Assigned Pfam label(s) PF10307- CL0029- CL0255- CL0137- PF18143

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2K2DEX1 572-752 None
A0A522CCL5 4-216 None
R6ZFP6 12-144 None
A0A3T0Y3R3 1-166 None
A0A3M1TL99 132-273 None
A0A395SZU8 6-204 None
G4TY20 19-156 None
A0A3M1CLQ6 34-191 None
A0A2M7W312 57-267 None
A0A0S6XPK8 10-159 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.