DPCstruct | MC18402

Metacluster Properties and Pfam Annotations

Number of structural domains2711
Mean domain length (aa)188 ± 38 aa
Standard deviation of domain lengths37.58
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.68
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.68
Pfam Score93.39
Assigned Pfam label(s) PF10307- CL0029- CL0255- CL0137- PF18143

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7U4UDJ0 40-231 AQQAPIHWVSVTQIAKSLDGLPPMAVGFDIDDTLLFSSPGFYRGKQEFSPNDESYLKNPAFWEKMNNGWDAFSVPKELGKALIAMHL…
A0A842M081 2-171 IRAVIFDLDGTLTEFNVRVGEVKRAIGCGEMPILEFLETLDEEKRRRAERILREEEIRAAKSCELKKGVKELLENLRRRGLRLAILT…
A0A2B4SR15 441-673 None
A0A5N9AI46 5-228 None
A0A5N9AIE2 2-205 None
A0A5C6T212 378-646 None
A0A7I8KN62 1-204 None
K8EIK8 15-199 None
A0A7I8KX04 8-158 None
A0A1T4NXI3 4-198 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.