DPCstruct | MC18370

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)193 ± 8 aa
Standard deviation of domain lengths8.17
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score88.92
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)18.87
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S8EZP0 108-285 AWERCRATINSSSVKSLNLSLFAYRLSISGPDFSKIGYLLNTKRITARLDPTHPHAAEYVPEDDEIILKSLPSDQLDRSFIVHEAVH…
A0A1W9QU75 1-208 MSALTDIVKVLRSPGCQNINFQYKNIKVSGSGFRKIASEILLGHIKIVSSFTVPSNAAKYNFIYNYLVTGIFPEKNLIVHECTHALN…
A0A6G6YMH5 1-192 None
A0A4Q3R0X7 21-213 None
A0A4V2NKI5 5-202 None
A0A653ZI27 10-198 None
A0A0D1EMB3 30-224 None
A0A3A0DUX8 229-418 None
A0A5D0V8K0 127-332 None
A0A4Q0S4K8 99-285 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.