DPCstruct | MC18364

Metacluster Properties and Pfam Annotations

Number of structural domains7094
Mean domain length (aa)107 ± 20 aa
Standard deviation of domain lengths20.33
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score82.15
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)13.20
Pfam Score77.52
Assigned Pfam label(s) CL0110- PF09912- CL0203- CL0692- CL0103

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A399Z0J9 56-153 None
A0A5Q0CG28 2-92 None
A0A5F0GLZ2 84-200 None
A0A521TIZ3 256-359 None
A0A4Q5ZY98 1-147 None
A0A7Y1SSQ9 73-196 None
A0A533ZCP5 25-147 None
A0A0M8MIW3 8-102 None
A0A1Y4S1E7 589-725 None
A0A7V6TKU1 237-323 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.