DPCstruct | MC18364

Metacluster Properties and Pfam Annotations

Number of structural domains7094
Mean domain length (aa)107 ± 20 aa
Standard deviation of domain lengths20.33
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score82.15
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)13.20
Pfam Score77.52
Assigned Pfam label(s) CL0110- PF09912- CL0203- CL0692- CL0103

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z2JIK4 94-176 EQVHRGVKGFVRDLQGNPIFNASVSVEGIDHDMTTAKDGDYWRLLAPGNYKVGASAPGYLTVIKKVAVSYSPATRVDFELESL
A0A7C5YKB2 17-116 FGCLGFNNGKLTPGIFGQVISKGTRQPIANATVSLRRDGNELASVQTNGDGRFAFPNLEPGTYLLVVSANGYWDAQVWVTLAQGQRL…
A0A519NIL3 834-931 None
A0A662TXP5 125-228 None
A0A655U4M1 234-310 None
A0A0R2FXA3 818-943 None
A0A534N6K4 1-90 None
A0A7W1C1F0 96-211 None
A0A7C2BKX9 167-295 None
A0A517TY43 283-405 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.