DPCstruct | MC18362

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)157 ± 9 aa
Standard deviation of domain lengths9.08
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score85.83
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)38.11
Pfam Score100.00
Assigned Pfam label(s) CL0033

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A834M6B2 38-197 IPILVSAAFLQMEPLLHDCLLYCHQHMNEILRTATNLNCLNDSVLTRLAAMYTNTEVESIKDRKDKIQSRLFAKLIQSLAEPDPESV…
A0A4W5RF80 1-150 MDTLVEECIQYCHKHMSAIVATPCNMNCINSNLAAHISDLFSHNEADDVMDRKDKFKSKLFQKKIECLFNPDYKNQDSPGNASTLYR…
A0A4Y2MTT5 27-184 None
A0A6A5CFF5 199-327 None
A0A812JPC2 16-171 None
A0A672KCF6 120-282 None
A0A7I8VY82 210-370 None
U4UF21 274-433 None
A0A6J3C0S6 329-488 None
L9KK55 118-290 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.