DPCstruct | MC18360

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)86 ± 7 aa
Standard deviation of domain lengths7.02
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score91.01
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)38.10
Pfam Score100.00
Assigned Pfam label(s) CL0369

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W5RCU6 1-94 MADRSQHEELTELPDLSGFLREDPYLAPYQEDLCRRYQLFTERLSKLQEAEGSFDAFTRSYMSYGVQRQADNSLMFREWAPGAQALF…
A0A2R7W8Z1 8-94 LDPMEVEVPELQNLLERDPYLKPYEREFRRRYAVMMDSLERIENDFGGYAKFLSSYRTYGIHVKSDNSVECAEWAPGAIQLYLTGEF
A0A813A882 4-75 None
A0A2J7ZY55 130-217 None
A0A811VCW5 5-88 None
L1I501 21-108 None
A0A453BXI9 83-184 None
A0A2P4Z9T7 1-92 None
A0A1Z5SL44 12-90 None
A0A5B7DF27 8-94 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.