DPCstruct | MC18355

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)110 ± 8 aa
Standard deviation of domain lengths8.03
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score61.58
Mean fraction of residues predicted as intrinsically disordered0.60
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)54.03
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W5PEA1 1-124 RFYCKSGRWQHRARDDISKWSLAMGLGDHDLLTCGQCQMNFPLGDILLFIEHKKKQCQTLLQGPGCYDKMQQQNQGRHVHSQLRKVV…
A0A4W5R029 1-123 MRKRERVEGLRACSVVSLSLCHLAMGLVDHDLLTCGQCQMNFPLGDILLFIEHKKKQCQTLLQGHGCYDKMAQQQNQGRHGHCQLRK…
A0A673K7Z8 20-123 None
A0A2D4PMQ6 34-143 None
A0A3B3UCU7 1-104 None
A0A3N0Y629 26-131 None
A0A673ZS63 1-102 None
A0A673U0A9 30-139 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.