DPCstruct | MC18354

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)159 ± 25 aa
Standard deviation of domain lengths24.59
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score75.07
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)35.70
Pfam Score84.62
Assigned Pfam label(s) CL0396- CL0416

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J8DQ10 127-260 VNCWETKVGNELYRLVLIDFIFILGATFFLEFIHKIMANYCCTKALKEPEFDIGRNTLDLIYSQSLCWFGTFYSPLLSVMMIVKLFI…
A0A4W5QVW8 1-141 MSILGILCYYWMKDVANTFSCWESIVGQALYRLVIVDFLFIMLGSFFGEFLSNVIGTKCIQSLGVPEFDVARNVLDLIYAQTLAWIG…
A0A7R9IUX9 388-541 None
A0A0V0ZB63 233-378 None
A0A1S3J8Q4 75-222 None
A0A482VU33 258-409 None
A0A7R8X135 351-536 None
A0A7J6D873 182-338 None
A0A2T7PUD8 65-225 None
A0A5E4AFM1 1-197 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.