DPCstruct | MC18337

Metacluster Properties and Pfam Annotations

Number of structural domains71
Mean domain length (aa)260 ± 45 aa
Standard deviation of domain lengths45.20
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score85.60
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)22.48
Pfam Score80.23
Assigned Pfam label(s) CL0020- CL0236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5E8AQ27 2-159 LLLMKAACLERLMELNTLGPADSLTRFLEAQFVINAAHLDSIYDAIGRATTAQVRRNFEAIYAAGVDEYYPGVTGDLIEQLHTALGS…
E1TJ96 338-604 FDAALALALQAAASPESEEEQQRVARMLPRLRRKLGEPAVRVRAERAAERSTLILPRPQASASQYAPSPEATHAPPSVEYLVRDHLT…
A0A0R3UE86 48-438 None
A0A2G8LPJ1 409-680 None
R9PLR4 679-903 None
A0A158R4T1 625-914 None
A0A349X2E2 17-206 None
B7Q630 239-535 None
A0A4R1PLJ1 117-343 None
A0A094JEZ8 14-266 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.