DPCstruct | MC18298

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)301 ± 44 aa
Standard deviation of domain lengths44.34
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score81.38
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)26.21
Pfam Score100.00
Assigned Pfam label(s) PF01970

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A2IHD0 8-396 EMIAASVFGAVLYTIIGIAPGTDETAVLAPVTLVLVLTGMEPIVILAFFISAIVAKKLTDSIPVAIAGIPGGVMSAPMVEHAMVLKK…
Q6LNJ8 2-288 LDGILSGLSTAIMPTNLMMVMVGCFVGTFIGMLPGLGPISAIALMIPISYGLDPASGLILMAGVYYGAVFGGSTSSILINAPGCSST…
A0A2E3QLX5 2-347 None
A0A812T3Q8 791-1081 None
A0A1Y5SHZ1 46-324 None
A0A395YH52 15-312 None
A0A4Y9VC92 739-1069 None
A0A0J9EBS4 6-329 None
A0A1Z2SKD8 2-337 None
A0A843JC95 8-284 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.