DPCstruct | MC1825

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)205 ± 39 aa
Standard deviation of domain lengths38.79
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score69.38
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)40.87
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S7M3D3 236-404 QDEDDEDLESEDVFEPNLPQKEHSNHNSYSWCLMRLAMVQLVLVNLKSFYPMAGYDLLDLPVASPLCHAVLKTLQRWEQVLQKRLEL…
A0A183J520 1-244 MTDSDSDIEHEPAVAAKIQQQQSYLDPNSYAWLILRLALVRQAFYRVKQFVGLCGLDFSEIGTQSPLIRCSLLTLEEWMYSITAELD…
A0A0S7M2W5 134-302 None
A0A1I7WD23 591-807 None
A0A3P7FPV9 833-1092 None
A0A7J8IHF2 813-967 None
A0A1U8CUH3 2-182 None
A0A158Q409 1295-1540 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.