DPCstruct | MC18246

Metacluster Properties and Pfam Annotations

Number of structural domains106
Mean domain length (aa)104 ± 14 aa
Standard deviation of domain lengths13.91
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score85.04
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)29.97
Pfam Score96.88
Assigned Pfam label(s) PF12571- CL0064- PF10983

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1X7NWA9 14-129 None
A0A0A8K5D9 12-135 None
A0A497PQJ0 53-182 None
A0A0A1PNH9 96-197 None
A0A6N1VDI3 20-117 None
A0A0P6WI96 13-118 None
E2CNP3 23-127 None
A0A7W9JWF7 8-126 None
J7Q4A7 22-132 None
A0A1S7RZC7 65-159 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.