DPCstruct | MC18246

Metacluster Properties and Pfam Annotations

Number of structural domains106
Mean domain length (aa)104 ± 14 aa
Standard deviation of domain lengths13.91
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score85.04
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)29.97
Pfam Score96.88
Assigned Pfam label(s) PF12571- CL0064- PF10983

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K6E2V0 156-260 SAQKINTEIYNAIRGLEWQDSVKSKTITAPPASPIKNDRYLIPSNATGAWSGKGDQVVHYNGAAWEYYVPNLGWSIYVDSENKNYVY…
A0A7Y2IZW1 3-78 LTLASRAITAPPGTAEEGACYAVPAGAVNAWDGQAGRLALFVGGGWDFLDPVTGWRAWIADEGVPGVFDGVDWVAG
A0A250KPR8 6-87 None
A0A3C1GAA7 116-205 None
A0A2E1CTG0 30-132 None
A0A7C3V220 51-157 None
A0A1A9G110 56-156 None
A0A1Q3WRE6 9-115 None
A0A2G2MSN0 22-130 None
A0A2T5G036 115-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.