DPCstruct | MC18238

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)128 ± 26 aa
Standard deviation of domain lengths26.32
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score75.46
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)33.36
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W2PUU4 96-234 GQSTTKVARAKKKGSQSLAAIWFEWFTAEPRVYASPVVKKTTLYEFRHITGYMMLFLPTGFALDVASPAYKDEVLALGDKARKSALE…
A0A6G0LX77 10-136 AASKTAAATWFEWYTKTPRIWEVCDDRQYKYQPKQIVAYMKLFHPLGFSLDPTTREYADRVMQAGNTAQKNMHEFLQARGIKRKFGS…
G4ZDT1 126-267 None
A0A2P4YT49 5-216 None
K3WYX6 21-144 None
F0WNH4 28-158 None
A0A225WJF7 432-567 None
A0A6A4C2P1 410-545 None
W2P544 1-105 None
A0A2P4YTU5 4-110 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.