DPCstruct | MC18214

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)107 ± 11 aa
Standard deviation of domain lengths10.60
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score80.05
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)40.46
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q4S863 14-138 MSVSGLKAELKFLESIFDPNHERFRIIDWKPDELSCQFNVTGDKLLIIHCNITESYPSTPPIWFVDSDDPSLAQVLERLDDVRRGST…
A0A0B6ZX54 4-103 LARLKEDIRVLETAFPRVHNRFQVLTATVDELTCRFIGRNGEKFDVQANITETYPQTAPIWFSDSEDASTLGIVGELANTKPEQFNI…
A0A3Q0KDU0 4-102 None
A0A310S6R1 4-105 None
A0A132AIM4 1-128 None
A0A3Q7W4Q5 1-96 None
A0A6I8R5V5 3-104 None
A0A3Q0JJP6 4-105 None
A0A1X7U203 5-110 None
A0A2A2LYP0 156-262 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.