DPCstruct | MC18212

Metacluster Properties and Pfam Annotations

Number of structural domains417
Mean domain length (aa)221 ± 51 aa
Standard deviation of domain lengths51.08
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score85.37
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)17.45
Pfam Score87.95
Assigned Pfam label(s) CL0125- CL0257- CL0099- PF00696- CL0039

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1U8EHR1 1-145 None
A0A4S4EW06 39-198 None
A0A255PAF6 123-276 None
A0A7H4SAC1 7-142 None
A0A7J3ZAK1 2-167 None
A0A2P6W3W7 64-267 None
R6Z1Q8 54-219 None
A0A2T2R641 4-211 None
A0A6C2YI11 16-216 None
A0A7Y5TYA5 5-179 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.