DPCstruct | MC18212

Metacluster Properties and Pfam Annotations

Number of structural domains417
Mean domain length (aa)221 ± 51 aa
Standard deviation of domain lengths51.08
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score85.37
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)17.45
Pfam Score87.95
Assigned Pfam label(s) CL0125- CL0257- CL0099- PF00696- CL0039

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453GEG9 1-213 MKFGGSSVSSAARMKEVAGLIQAFPEERPVVVLSAMGKTTNLLLLAGEKAVGCGVTRVSEIEEWNMLRDLHIKTVDELGLPRSVIHA…
U5RT38 20-241 KNVAKTVVSRVENGDSLVVVVSAMGDTTDDLIALSKKITDTPDKRELDALLSTGEMMSCALLAMAIKDLGYDAVSYTAYQIGIKTSG…
A0A2N9IBZ4 513-751 None
A0A0B8PDK9 61-296 None
I1CK30 2-176 None
W7C657 128-411 None
A0A520R111 26-198 None
A0A7J6L3W9 24-306 None
A0A068UWC2 123-289 None
A0A7X7KVH2 15-159 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.