DPCstruct | MC18181

Metacluster Properties and Pfam Annotations

Number of structural domains176
Mean domain length (aa)283 ± 44 aa
Standard deviation of domain lengths44.36
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.78
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.41
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)16.06
Pfam Score95.16
Assigned Pfam label(s) CL0023- PF06527- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2N1C3E4 6-299 INHQLLLRPKVNRSESFQSYLIRLARANGYVYTAFSSEITAKSKPHRSMKLADRKEIQTLFKSISDPNVSELTDIWECAHYHKQQFD…
A0A7Y0HNP3 4-271 KLTVRLEIFRDESISSYIFRVSKENGLSYLAFWNMIKSSTKDYAQFSEINILDIAPLGHIDRDSYEERTGYSSESLINNSFYKVLEK…
A0A3N1IU36 10-353 None
A0A420D6S0 8-291 None
A0A5C6VAN9 2-293 None
A0A1I5L4E5 19-245 None
A0A2A3YHW8 15-323 None
A0A2N3VRF4 260-584 None
A0A4R7QN78 547-928 None
A0A4Q9KE46 111-401 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.