DPCstruct | MC1818

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)75 ± 4 aa
Standard deviation of domain lengths3.66
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score89.04
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.95
Mean intra-cluster sequence similarity (%)40.93
Pfam Score100.00
Assigned Pfam label(s) PF07774

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q2H523 150-232 ITHERDVLGVEKIITAPAIVESTSLVFAYGIDVFGTRVAPSFLFDILGKGFNKVALVGTVLALLAGVLMLAPVVRRKQINLRW
A0A183ITD3 1-72 MRTFPSGLESTSLLFVAGLDLFFNRVSPSGTFDILKEDFDHWFISFVLLSLLLASLLSKRLAKQKDLKQSWR
Q1WMU7 70-142 None
A0A1S8WZW8 291-364 None
A0A183K9X9 375-448 None
A0A0D8Y9K6 30-101 None
A0A7S2UA25 84-157 None
A0A0P0WJT6 661-734 None
A0A6U4TBM4 60-133 None
A0A812S558 328-401 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.