DPCstruct | MC18168

Metacluster Properties and Pfam Annotations

Number of structural domains489
Mean domain length (aa)125 ± 19 aa
Standard deviation of domain lengths18.56
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score85.02
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)31.62
Pfam Score99.28
Assigned Pfam label(s) PF01412- CL0154- CL0110- CL0080- CL0192

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H2IYU9 154-282 None
A0A2P4YUA2 145-281 None
A0A1X2I5Y6 52-203 None
A0A195CX09 765-899 None
A0A6F9CNU7 5-76 None
A0A672GFR1 437-560 None
E3K1K4 823-934 None
A0A5J5UCJ2 6-96 None
A0A194R4T8 6-138 None
T1GBX7 5-97 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.