DPCstruct | MC18168

Metacluster Properties and Pfam Annotations

Number of structural domains489
Mean domain length (aa)125 ± 19 aa
Standard deviation of domain lengths18.56
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score85.02
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)31.62
Pfam Score99.28
Assigned Pfam label(s) PF01412- CL0154- CL0110- CL0080- CL0192

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A671NUV5 6-126 AEALSNYEVAERIWAEPSNQMCADCSDAKPEWAAINLAVVFCKRCAGEHRGLGPSISKVRSLKMDKKVWSEDLIQVCLVYVRVLYEA…
A0A453BA28 4-72 QILEGLLRLPENRECADCKSKGPRWASVNIGIFVCMQCSGIHRSLGVHISKVRSATLDTWLPEQVAFIQ
A0A0B0P9A8 1-130 None
A0A1V2LK23 384-525 None
F4Q4Y9 3-138 None
A0A4Z2HJI2 2-110 None
M2Q6E3 918-1036 None
Q5KAL5 1038-1172 None
A0A7M5VD33 622-744 None
A0A504X3Z6 5-149 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.