DPCstruct | MC18165

Metacluster Properties and Pfam Annotations

Number of structural domains204
Mean domain length (aa)162 ± 35 aa
Standard deviation of domain lengths34.70
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score91.56
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)22.04
Pfam Score97.67
Assigned Pfam label(s) CL0193- CL0020- PF07715

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C5S415 324-467 LVFDPHIPSLIMGAGNTPQEIRMSGVRVNKFEVRRGAMADLSNDFPIFRYADILLMKAEALIRQGKNGDEYVNQIRNRAGLGNWTNV…
A0A7T9Q4D5 42-194 DADTEIPFNVKQKHANSFQSGDHFYLLRLADIILLKAEAQNALGNTSGAINTINVIRHRAGLSDLSGVSSSALKAIILNERRLELAF…
A0A2N2ARF6 235-341 None
A0A350YXS9 28-191 None
A0A258E9C6 99-254 None
A0A3C0ZB86 37-208 None
A0A3C0RW96 125-292 None
A0A7X7BZF7 81-249 None
W4PKI5 13-139 None
A0A1G6PHD6 570-695 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.