DPCstruct | MC18137

Metacluster Properties and Pfam Annotations

Number of structural domains48
Mean domain length (aa)134 ± 24 aa
Standard deviation of domain lengths24.42
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score80.60
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)41.16
Pfam Score97.37
Assigned Pfam label(s) PF17846- CL0036- CL0280

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2G5CKC9 81-194 QFLNIFVLREYLQYDLDIPNPPFEINFERILDDFVFLCFFVGNDFLPHMPTLEIREGAITLLMYIYKREFASMGGYLTDAGEVLLGR…
A0A2G2VGP1 341-471 VLREYLQYDLEIYNPPFQIDFERVVDDFVFLCFFVGNDFLPHMPTLEIREGAINLLMFIYRRDFTTMGGYLTDAGEVFLDRVEHFIQ…
A0A816CND5 107-243 None
A0A7S3PKU7 18-136 None
A0A6P3Z399 10-122 None
A0A0R3QFT5 107-196 None
A0A0D9XP87 2-116 None
A0A446Q6Y1 229-405 None
L8YF78 117-279 None
A0A2G5DN20 194-308 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.