DPCstruct | MC18125

Metacluster Properties and Pfam Annotations

Number of structural domains44
Mean domain length (aa)156 ± 32 aa
Standard deviation of domain lengths31.60
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score75.92
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)24.37
Pfam Score92.42
Assigned Pfam label(s) CL0187- CL0214

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S3A615 37-191 GPSGRDGGACNLYILHEVGDTDTIQGLSLRYEVDTDLICRYNALMSQHHLTHRSQVFIPVVHEEQRMWYKEKTGDIVYDPHVGREYV…
A0A6M2E6T8 184-326 AISHKIVKGDSVASLAVKYSVQVMDIKRINNMTSDHGIYSRERLLIPIINPNLLINETCYIELDTYANREVAVLYPEGKPDEKLMSK…
A0A822XK52 1-140 None
A0A423X9I1 588-749 None
A0A194VPF9 78-219 None
A0A6D2L748 335-468 None
G3J7F7 5-133 None
A0A7S4P1W7 26-148 None
A0A2K1J788 332-467 None
A0A146IMP5 167-355 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.