DPCstruct | MC18107

Metacluster Properties and Pfam Annotations

Number of structural domains32
Mean domain length (aa)132 ± 18 aa
Standard deviation of domain lengths18.05
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score91.82
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)34.62
Pfam Score94.44
Assigned Pfam label(s) CL0139- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V2EX02 230-369 HPESIVHSLVSFADGAMMAQLGYPDMKLPIQLALTYPERLPCVKQLDLVSLGALHFYPLPKEKFPCYSLALAAGKAGGTAPTVLNAA…
A0A6M8W9B9 3-107 RARKAAQRALDWHRLGRLDFCEPDAGRFPAIGLAMDVIRRGGGAGAVLNAANEVAVEAFLAGDIPFGRIVEIVGETVARVSSDRGES…
A0A7V5KX67 11-119 None
A0A1F8LM19 161-305 None
A0A834SZW7 77-190 None
A0A3M0Y3N0 1-128 None
A0A7J6U9H5 577-726 None
A0A7V5C3S6 253-376 None
A0A1Y5IQX7 164-309 None
A0A655N0F8 22-144 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.