DPCstruct | MC18075

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)204 ± 33 aa
Standard deviation of domain lengths32.97
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.63
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)30.28
Pfam Score91.82
Assigned Pfam label(s) CL0028- PF12551

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R1HK26 2-199 SEETTRIPGLQTVWQLATQVGRIASTTAGLAGETGRVVAGTSEVEPEKGDKRFRDPTWDDHPLYRRLKQEYLACQQAIDGFVKGADL…
A0A2T6A3J5 13-161 QAPGKQMELGVKAGRKWQRLMAHLMASAMDPQAAPVITPLPGDRRFAGEAWAKPPFSWMSQAFLLQQQWLHNVTHEVPGVTKHHEDV…
A0A349W9D4 2-213 None
A0A7I7NVD1 2-170 None
A0A0F3R8F7 4-191 None
A0A558HWZ0 35-261 None
A0A7X5BA23 51-252 None
A0A4R6YB10 186-372 None
A0A060NNB7 2-288 None
A0A812VQC3 609-809 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.