DPCstruct | MC18066

Metacluster Properties and Pfam Annotations

Number of structural domains132
Mean domain length (aa)99 ± 16 aa
Standard deviation of domain lengths16.33
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.98
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)20.96
Pfam Score91.67
Assigned Pfam label(s) PF07927- CL0219- CL0057

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R3Y6G3 1-81 MSKLDKLKKKLYKEPAPKDFTWDELKTLLLKLGFIEEQGSGSRVKFYHPELDYPINLHKPHPGNILKEYILKRIKETLDDL
A0A7C8IIE3 157-261 EAAPEQGPIIVDKRAQRVFKALFHSPNSPDQPGEIAWPDFLHAMVSTGFSAEKLQGSAWQFTPRSLDVERSIQFHEPHPGNKLPFTW…
A0A3M7H473 249-356 None
A0A3D4GNQ8 14-97 None
A0A5C2SQD4 593-701 None
A0A2V1DFB5 600-709 None
A0A4S9KG94 406-490 None
A0A853F3C9 58-140 None
A0A081BRU8 1-100 None
A0A6J5Z7Z7 6-88 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.