DPCstruct | MC18050

Metacluster Properties and Pfam Annotations

Number of structural domains387
Mean domain length (aa)144 ± 30 aa
Standard deviation of domain lengths29.76
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score76.62
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)14.13
Pfam Score81.85
Assigned Pfam label(s) CL0291- PF01390- PF01967- PF17619- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0M3J6G2 1-115 LEIRVTERDGDKLIYSSDYGSPNSPNYVDIVDKFKKGLGELIKKTTSGPSFVADDVNYITNPKIKNSTWDKGLLVNATADFKSPVDK…
A0A2D4L877 19-153 ASPQTTLPPTSKPPVATECFTINFIATNLIYRPQMANPKSKIFSSTQRYFVNLLRDILKNSDIGPDLINCRLSTLRSVNQKRYSGVD…
A0A2B4S9F6 302-412 None
A0A5N3W625 9-151 None
K7F747 133-299 None
C3ZG05 550-671 None
A0A1S3Q112 282-476 None
A0A6P8HK90 330-478 None
A0A2B4SQY7 390-531 None
A0A2B4SDW3 211-326 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.